于桂洪
2023-02-22 23:16:52 来源：betway必威 浏览数：0
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职 称：副教授 |
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公司系所：betway必威，微生物系 |
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学科领域：微生物学 |
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联系电话：18300234936 |
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通讯地址：青岛市城阳区长城路700号 betway必威/科技楼3037房间 |
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个人简介： |
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于桂洪，博士，副教授，硕士生导师。主要从事微生物代谢潜力挖掘、天然药物的发现、生合成途径和代谢产物的应用研究。 |
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教学工作： |
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1.本科教育： 微生物学（双语）。
2.研究生教育：生物学、生物与医药。
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科研方向： |
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微生物代谢及分子生物学研究。 |
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科研项目： |
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1.国家自然科学基金--青年科学基金项目（41806167）：“基于混合培养的海洋来源微生物代谢潜力挖掘及活性次级代谢产物研究”(25万，主持人，2019.01-2021.12)。
2.中国博士后科学基金--博士后面上项目（2017M622286）：“南极深海来源真菌PRB-2的次级代谢潜力挖掘”(5万，主持人，2017.11-2019.07)。
3.青岛市应用资助研究项目：“生物信息学指导下一株南极来源真菌代谢产物结构及活性多样性研究”(5万，主持人，2017.12-2019.07)。
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发明专利： |
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一种吲哚生物碱类化合物及其制备方法和用途，CN 106892854 B。 |
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代表性论文： |
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1.Xiaoxuan Ge; Yu Wang; Chunxiao Sun; Ziping Zhang; Lin Song; Lingling Tan; Dehai Li; Song Yang; Guihong Yu*; Secondary Metabolites Produced by Coculture of Pleurotus ostreatus SY10 and Pleurotus eryngii SY302, Chem. Biodiversity, 2022, 19: e202100832 (SCI 三区, IF = 2.745 )
2.Guihong Yu; Peng Sun; Reyilamu Aierken; Chunxiao Sun; Zhenzhen Zhang; Qian Che; Guojian Zhang; Tianjiao Zhu; Qianqun Gu; Mingyu Li; Dehai Li ; Linear polyketides produced by co-culture of Penicillium crustosum and Penicillium fellutanum, Mar. Life Sci. Tech., 2022, 4, 237-244 (SCI 二区, IF = 5.000 )
3.Guihong Yu, Yuman Sun, Heyang Han, Xiu Yan, Yu Wang, Xiaoxuan Ge, Bin Qiao, Lingling Tan*. Coculture, An Efficient Biotechnology for Mining the Biosynthesis Potential of Macrofungi via Interspecies Interactions. Front. Microbiol., 2021, 12, 532. (SCI 二区, IF = 4.235 )
4.Guihong Yu, Zichao Sun, Jixing Peng, Meilin Zhu, Qian Che, Guojian Zhang, Tianjiao Zhu, Qianqun Gu, and Dehai Li*. Secondary Metabolites Produced by Combined Culture of Penicillium crustosum and a Xylaria sp. J. Nat. Prod. 2019, 82, 2013−2017. (SCI 二区, IF = 4.257 ).
5.Guihong Yu, Qiuying Wang, Shan Liu, Xiaomin Zhang, Qian Che, Guojian Zhang, Tianjiao Zhu, Qianqun Gu, and Dehai Li*, Methylsulfonylated Polyketides Produced by Neosartorya udagawae HDN13-313 via Exogenous Addition of Small Molecules. J. Nat. Prod. 2019, 82, 998−1001. (SCI 二区, IF = 4.257).
6.Guihong Yu, Guangwei Wu, Zichao Sun, Xiaomin Zhang, Qian Che, Qianqun Gu, Tianjiao Zhu, Dehai Li, Guojian Zhang*, Cytotoxic Tetrahydroxanthone Dimers from the Mangrove-Associated Fungus Aspergillus versicolor HDN1009, Mar. Drugs, 2018, 16: 335. (SCI 二区, IF=3.772).
7.Guihong Yu, # Shuai Wang, # Lu Wang, Qian Che, Tianjiao Zhu, Guojian Zhang, Qianqun Gu, Peng Guo*, Dehai Li*, Lipid-Lowering Polyketides from the Fungus Penicillium Steckii HDN13-279, Mar. Drugs, 2018, 16: 25. (SCI 二区, IF=3.772).
8.Guihong Yu, Yanjuan Wang, Rilei Yu, Yanyan Feng, Lu Wang, Qian Che, Qianqun Gu, Dehai Li, Jing Li, Tianjiao Zhu*, Chetracins E and F, cytotoxic epipolythiodioxopiperazines from the marine-derived fungus Acrostalagmus luteoalbus HDN13-530, RSC Advances, 2017, 8: 53-58. (SCI 三区, IF = 3.049).
9.Guihong Yu, Guoliang Zhou, Meilin Zhu, Wei Wang, Tianjiao Zhu, Qianqun Gu, Dehai Li*. Neosartoryadins A and B, Fumiquinazoline Alkaloids from a Mangrove-Derived Fungus Neosartorya udagawae HDN13-313. Org. Lett., 2016, 18, 244-247. (SCI 一区, IF = 6.579).
10.Guihong Yu, Guangwei Wu, Tianjiao Zhu, Qianqun Gu, Dehai Li*. Cladosins F and G, two new hybrid polyketides from the deep-sea-derived Cladosporium sphaerospermum 2005-01-E3. J. Asian Nat. Prod. Res., 2015, 17, 120-124. (SCI 四区, IF = 1.009).
11.Guangwei Wu,§ Guihong Yu,§ Tibor Kurtan, Attila Mandi, Jixing Peng, Xiaomei Mo, Ming Liu, Hui Li, Xinhua Sun, Jing Li, Tianjiao Zhu, Qianqun Gu, Dehai Li*. Versixanthones A-F, Cytotoxic Xanthone-Chromanone Dimers from the Marine-Derived Fungus Aspergillus versicolor HDN1009. J. Nat. Prod., 2015, 78, 2691-2698. (共同第一作者, SCI 二区, IF = 3.662).
12.参与编写《海洋天然产物与药物研究开发》一书。
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